DMG supplement sublingual 100 mg, 125 mg 500 mg benefit side effects Dimethylglycine, dosage, tablets, latest information by Ray Sahelian, M.D. December 22 2017. If you find the field of mind-boosting pills, sex nutrients, and anti-aging interesting, you will certainly want to learn more about DMG (dimethylglycine), TMG (trimethylglycine), and methyl donors. If you're going to do TMG, make sure your supplementing Taurine as. Do taurine for a week before introducing the TMG. A good DAN doctor should be able to tell from test results if DMG. TMG is the way to go. Gfcfmom wrote: Thanks. I have my son on DMG right now with added folic. B12 from Kirkman. Learn more about Dimethylglycine uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Dimethylglycine.

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DMG: A Nutrient for the New Millennium

DMG, short for dimethylglycine, is a nutritional supplement that can provide wonderful positive benefits to humans and animals. Our bodies use DMG every day, even though we don't know it. Humans and animals produce DMG in small amounts, and it affects nearly every metabolic pathway within each cell of the body. At the end of this paper, I will include the more technical, scientific information for those intrepid individuals who wish to learn more.

Here is what you need to know about DMG:

It provides useful building units for biosynthesis of vitamins, hormones, neurotransmitters, antibodies, nucleic acids and other metabolically active molecules. It can be helpful in virtually all species of animals, including dogs, cats, rabbits, ferrets, rodents, reptiles and birds.DMG is one of the nutrients found in the supplement, Immune and Digestive Support. Many veterinarians have discovered the unique and wonderful properties of this new supplement.

Laboratory and clinical research indicates that DMG supplementation can be used effectively as a nutritional adjunct to a number of health issues in pets.

These include:
Cardiovascular problems
Glucose metabolism
Autoimmune disorders
Allergies
Cancer/tumors
Liver diseases
Respiratory problems
Immune response deficiencies
Neurological disorders
Neurological disorders

Let’s look at many of the specific conditions that Immune and Digestive Support containing DMG may help your pets.

DMG for Seizuring Animals

Ferrets with Insulinoma

DMG increases the threshold for seizures and can reduce seizures in all types of animals. In some cases, if DMG is added to a seizuring animal’s therapy, it may decrease the amount of anticonvulsants required by an animal. This can be very beneficial for ferrets suffering from insulinoma, until the blood sugar issues are under control. Diet plays a huge role in helping stabilize a ferret suffering from insulinoma, and Young Again Ferret Food is one very positive step in improving the health of a ferret. In some cases, an insulinoma may present as a solitary tumor in the pancreas, but for most ferrets, the lesions are microscopic infiltrates, and surgery is not considered the best way to treat this condition. Some veterinarians recommend surgically removing approximately 1/3 of the pancreas, usually the tail of the pancreas, however, the pancreas is a delicate organ and surgery is not always beneficial.

DMG and the Immune System

It improves the immune response by increasing resistance to disease and infection.

It has antiviral and antibacterial properties. It can modulate the inflammatory response.

DMG and Tumors

A study was performed using mice and melanoma cells. Mice were injected with melanoma cells and those mice receiving DMG had fewer implantations of melanoma cells than the control group did. This study was performed at Baylor University.

It possesses anti-cancer activity and can prevent metastases (the spread of tumor cells). I routinely use DMG in all of my patients with any type of cancer. If it can help prevent the spread of tumors, then I am all for it.

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DMG and Cardiac Disease

It aids in cardiovascular functions by reducing elevated cholesterol, blood pressure and triglyceride levels and improving circulation. Ferrets and cats with cardiac disease may benefit from the administration of DMG.

DMG and Diabetes in Cats

It improves glucose metabolism and for this reason, I recommend prescribing DMG for all diabetic cats, in addition to changing the cat’s food to Young Again Zero Carbohydrate Cat Food. Many diabetic animals will eventually develop cataracts in the lenses of the eyes, which can significantly decrease eyesight. When the cataracts are mature, the diabetic pet will eventually lose vision, except for being able to discern light and dark. DMG can retard cataract formation in diabetic animals.

DMG and IBD/IBS

According to literature studies, DMG helps with inflammation, circulation, healing and detoxification, all of which helps cats and dogs suffering from inflammatory bowel disease and inflammatory bowel syndrome. Young Again pet foods may help contribute to the resolution of issues related to chronic gastrointestinal problems in dogs and cats.

DMG and Cataracts

DMG is also an excellent adjunct to therapy for rabbits suffering from E. cuniculi, which is a microscopic protozoal organism that has an affinity for kidney tissue and the central nervous system (CNS). In addition to strengthening the immune system, DMG may also slow the formation of cataracts in the eyes of E. cuniculi infected rabbits.

DMG and Liver Disease

It aids in detoxification and enhances liver function. When administered, part of it will be converted to SAM-E, a nutrient helpful to the liver. Any cat suffering from hepatic lipidosis from not eating for one or several days may benefit from the administration of DMG.

DMG and Exercise

It improves oxygen utilization in the body and it removes lactic acid from muscle tissue. This makes DMG wonderful for athletic dogs. Lactic acid is what causes muscle cramps and pain after running. I know that many greyhound racers use DMG for their dogs. Many horse trainers believe it is helpful during training exercise.

It enhances energy levels, endurance and muscle metabolism.

It improves mental and physical performance.

It improves neurological function and mental clarity.

DMG use in Veterinary Medicine

DMG has been used by veterinarians and trainers in horses and dogs.

DMG is suggested for use in dogs, cats, horses and birds for performance and enhanced recovery from illness. It can be used therapeutically as an adjunct to traditional therapy for osteoarthritis, stress, seizures, allergies, heart disease, cancer, feline immunodeficiency virus (FIV), feline infectious peritonitis (FIP) and diabetes.

DMG has antifungal properties and helps fight bacterial and viral infections. It is converted to SAM-E in the body. It helps detoxify the liver. It decreases the inflammation associated with IBD (inflammatory bowel disease). It helps maintain glucose metabolism and can help slow the development of diabetic cataracts. DMG helps circulation and cardiovascular health.

It increases the threshold for seizures and I have personally used it to control seizures in many animals, including dogs, cats, Amazon parrots, lovebirds and many other animals. In many cases, DMG alone will control seizures, and in other cases, reduced amounts of anticonvulsants will be necessary (such as phenobarbital, Valium, Keppra or phenytoin). It can be used for many neurological problems in exotic animals, such as idiopathic seizures in red-lored Amazons and peach-faced lovebirds, E. cuniculi in rabbits, PDD in psittacines and hypoglycemic seizures in ferrets (resulting from insulinoma issues).

While the label recommendation is for once or twice a day dosing, this supplement is absorbed rapidly, so often I will recommend small, incremental doses during the day. Often to help control seizures, I find that more frequent dosing will control seizures (along with treating any underlying medical problems, such as infection, low blood glucose or even lead toxicosis) much better than just one or two doses per day. I recommend working with your veterinarian to adjust the DMG and/or anticonvulsant medications to best control seizures.

The Science of DMG

As promised, I am providing a bit of the science (including the jargon) about how DMG works. DMG is an adaptogen that works with other cofactors in the body to counteract the negative effects of stress, to promote healing and even to help prevent some degenerative diseases. Some of the things that it does are to decrease homocysteine levels (a risk factor for cardiovascular disease), increases oxygen utilization, modulates the immune response, aids in liver detoxification, regulates cholesterol and triglyceride levels, and increases energy levels. New research shows that DMG can function as an antioxidant and prevent free-radical damage. So, you can see how this nutrient can be a wonderful adjunct to traditional medical therapy for many different disease states.

DMG is found naturally in low levels in the body, and also in certain foods, such as meat (liver), beans, seeds and grains. It is considered an intermediary metabolite, meaning that it is rapidly broken down into other substances that the body needs. The body can produce small amounts of DMG from other nutrients, but supplementation can provide increased levels of DMG resulting in many healthful benefits for the body. DMG is built from the amino acid glycine and is physiologically active and important to cell metabolism. It provides methyl groups for modification, building and detoxifying many components in the body. Biochemically, it occupies a central position in the cell's metabolic pathway, so it can produce a wide range of biological effects in the body.

DMG and the Autistic Spectrum

While I have no personal experience with autistic children, there are many testimonials describing significant improvement in autistic children that are given DMG regularly. Apparently, many autistic children will become more verbal and communicative when taking DMG, and may become more interactive with family members. Again, I have no personal experience, but with children being diagnosed with any number of problems within the autism spectrum in almost epidemic proportions today, it is worth a look-see in case it can help a child that you might know. I don’t see how it can be detrimental. The same can be said for animals suffering from abnormal behaviors, such as pacing, repetitive behaviors, obsessive licking or those suffering from other unusual situations.

It improves verbal communications and social interactions in autistic individuals. While there isn’t any research in pets suffering from separation anxiety or other issues, DMG is certainly a “do no harm” addition to any medical and behavioral therapy.

Dosing DMG

DMG should be taken between meals, although it can be taken with food. DMG is broken down quickly and used by the body, so smaller, multiple doses are better than giving the entire dose all at once. The upper limit of dosing is extremely high; humans can take up to 6000 mg. per day without complications or risk of overdosage.

DMG comes in a liquid and the dosage is right on the label, and the dosage is also marked on the dropper which is included. Vetri-DMG Liquid is available for use in small animals and exotics. Each drop contains 5 mg of DMG.

According to the label dosing, the dosage for birds is: 1 drop per 100 grams body weight. This is given BID as a loading dose, for two weeks, then once a day. The liquid may also be used for dogs and cats:

Give dosage two times per day for the first two weeks, as a loading dosage, then give once a day, or for best results, divide dosage between a.m. and p.m. However, it is a very safe supplement and I will often tweak the dosage to accommodate the situation and provide the best support for the animal. Smaller, incremental doses are seemingly much more efficacious than one dose once a day.

If you are interested in reading more about DMG, there is a wonderful book entitled Building Wellness Through DMG (by Roger V. Kendall, Ph. D. with Adena Therrien, Freedom Press, 2003) that explains the science behind the supplement. The book discusses using DMG for lupus and other autoimmune disorders, respiratory disorders, cancer and autism, to name just a few. There are also many scientific papers that you can explore on-line, as well. The book discusses dosages for humans and animals with different conditions that might benefit from the administration of DMG.

DMG is available from several sources. Some nutrition and vitamin outlets sell DMG for humans in a powder, liquid or tablet/capsule form. I purchase mine as capsule from Now Foods, Bloomingdale, IL 60108, www.nowfoods.com. Another source is Best Naturals, NJ, www.shopbestnaturals.com.

DMG is available in tablets for small animals and exotics from Vetri-Science Labs, phone number: 800-882-9993. However, Vetri-Science Labs sells only to licensed veterinarians. For pet owners interested in purchasing single bottles, check the web, as we have seen it offered at Amazon.com.

Copyright © 2006 Margaret A. Wissman, D.V.M., D.A.B.V.P.
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Description

Dimethylglycine (DMG) is a versatile, health-building, anti-aging and healing nutrient derived from the amino acid Glycine. It is very important for optimal health and is produced by all animals and humans in small amounts. Our bodies use DMG every moment of every day to affect nearly every metabolic pathway in the body. It’s a building block for the synthesis of methionine, choline, important hormones, neurotransmitters and DNA. Dimethylglycine is found in certain foods such as beans, pumpkin seeds and liver; however, nearly everyone can benefit from supplementing their diet with higher levels of DMG.

Feel Young Again, Age Gracefully

Dimethylglycine is known as one of the most effective anti-aging nutrient in the world. DMG helps you to feel young, vital, healthy and strong well into old age. It boosts strength, endurance and stamina by dramatically improving the nutritional environment of the cells. This in turn causes the tissues and organs of the body to function more efficiently and with more youthful vitality, no matter how old you are.

Aging decreases immunity, but dimethylglycine helps enhance immunity to slow the aging process. DMG helps us to age more gracefully. As we get older, free radicals and stress damage one’s ability to maintain immune system function, memory and physical ability. DMG helps us cope with stress, increases tolerance to physical activity and helps us fight fatigue as well as improving stamina, sexual function, athletic ability and mental acuity.

In her best selling book, Breakthrough: Eight Steps to Wellness, actress and best-selling author Suzanne Somers calls DMG a critical nutritional supplement. She is well into her 60s and is still radiant and stunningly beautiful. Dr. Ray Sahelian, M.D., bestselling author of Mind Boosters: Improve Your Mind, Memory, and Mood wrote, “If you find the field of mind-boosting pills, sex nutrients, and anti-aging interesting, you will certainly want to learn more about DMG (dimethylglycine).” He’s among many medical professionals that acknowledge the very pronounced benefits of dimethylglycine, such as increased energy, an overall feeling of well-being, faster thinking, enhanced memory and particularly greater stamina throughout the day. In other words, you don’t burn out as easily in the course of a normal day.

Numerous Health Benefits from Taking DMG

The health benefits from supplementing with DMG are significant. Dimethylglycine greatly improves the nutritional environment of the cell, increases immune system function (between up to 300% and 1000%) and improves oxygen utilization which enhances energy levels in the body. It helps to optimize mental activity and brain function and supports the body in counteracting the negative effects of mental and physical stress. DMG is one of the best anti-aging nutrients on the market.

Dimethylglycine is a major anti-stress nutrient, energy builder and adaptogen that benefits your metabolism, health and well-being. The average person has fatigue issues, injuries, gets sick and is generally stressed out. When the body is under conditions of stress, DMG improves oxygen utilization in the body and enhances cellular metabolism. Studies show that DMG supplementation helps both humans and animals adapt to increased physical activity by reducing blood lactic acid levels, increasing oxygen uptake by tissues, enhancing ATP production, normalizing glucose metabolism and decreasing fatigue. DMG reduces lactic acid build up in the muscle thereby shortening recovery time after strenuous exercise and improving endurance. Dimethylglycine:

• Helps stimulate and maintain a strong immune system
• Improves metabolism
• Optimizes energy levels
• Makes energy production more efficient
• Reduces lactic acid formation
• Minimizes cravings for alcohol and drugs
• Enhances detoxification of the blood and the liver
• Increases oxygen utilization
• Enhances methyl donation
• Acts as an adaptogen
• Enhances neurotransmitter production
• Improves circulation
• Helps the body adapt to stress
• Decreases homocysteine levels
• Increases glutathione and SAMe levels
• Decreases elevated blood pressure, triglyceride and cholesterol levels
• Acts as an antioxidant
• Promotes the neutralization of free radicals
• Has anti-inflammatory properties
• Provides building blocks needed for synthesis of important body constituents
• Supports lymphocyte production

In the nation’s #1 bestselling guide to natural remedies, Prescription for Nutritional Healing, authors James Balch, M.D., and Phyllis Balch, C.N.C. recommend using DMG for 48 condition-specific uses. DMG is useful in so many conditions in part because it is a metabolic enhancer. As Dr. Balch writes, “Taking supplemental DMG can have a wide range of beneficial effects, including helping the body maintain high energy levels and boosting mental acuity. DMG has been found to enhance the immune system, and to reduce elevated blood cholesterol and triglyceride levels. It improves oxygen utilization by the body, helps to normalize blood pressure and blood glucose levels, and improves the functioning of many important organs.”

How Does Dimethylglycine Work in the Body?

Dimethylglycine is an important methyl donor that participates in numerous biochemical pathways and is important for glutathione synthesis. It’s able to donate a methyl towards necessary enzymatic reactions. This ability to donate one of its methyls is very crucial in the synthesis and production of important brain chemicals. Sufficient levels of glycine in the body are responsible for a general overall feeling of health or well being.

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A methyl donor is simply any substance that can transfer a methyl group [a carbon atom attached to three hydrogen atoms (CH3)] to another substance. Methylation is a biochemical process that is essential to life, health and regeneration of body cells. Vitamins, hormones, neurotransmitters, enzymes, nucleic acids (DNA and RNA), and antibodies depend on the transfer of methyl groups to complete their synthesis. Scientists suspect that proper methylation of DNA may prevent the expression of harmful genes, such as cancer genes. Our body’s ability to methylate declines with age, contributing to the aging process, and therefore supplementation can be beneficial.

The versatility of Dimethylglycine to donate methyl groups and generate molecules like glycine, serine, sarcosine, ethanolamines, methionine and cysteine, as well as contributing to the formation of SAMe, may explain why DMG has such broad and wide-reaching therapeutic effects on the body. Some of those therapeutic effects include enhancing energy production, increasing circulation, decreasing seizure activity, reducing lactic acid levels, promoting better oxygen utilization, lowering homocysteine and many other beneficial effects.

Is DMG New?

Dimethylglycine in supplement form has been around for over 40 years with numerous clinical studies to prove its benefits and safety. DMG was first discovered by Russian scientists who were looking for a solution to the problem of accelerated aging in cosmonauts in space. Through performing hundreds of research studies, they found that returning cosmonauts who used DMG showed no symptoms of cellular damage or premature aging that the other cosmonauts all displayed.

How to make a bootable dmg usb in windows. Originally called “vitamin B-15” or “calcium pangamate” in the 1960’s and 1970’s, dimethylglycine has been cherished by top athletes and sports professionals for its ability to enhance performance and increase endurance. Olympic greats, world-champion body-builders, Super Bowl champions and the heavyweight champion of the world have all attributed their success in part to supplementing with DMG.

Aging and over-the-hill athletes notice especially good results from taking DMG. During an internationally televised interview with Muhammad Ali in 1976, the boxing champ held up a bottle of “B-15” (DMG) to show the world his “secret weapon.” As reported in the National Medical Bulletin in 1978, Ali took DMG during his many consecutive victories, and then when he stopped taking it, he was defeated by a newcomer. Once he began taking DMG again, he beat that same newcomer in a rematch in 1978.

Is DMG Safe?

Dimethylglycine has a long history of safe use by humans and is an intricate part of human metabolism. DMG is absolutely required by the human body to function optimally. DMG is hypoallergenic and is an extremely safe food substance that can enhance normal metabolic pathways in the body. It is safe for use in children of all ages. Doctors have been recommending DMG for autistic children since 1980.

Extensive animal studies on the safety of dimethylglycine showed that it is actually as safe as vitamin C. It is literally impossible to overdose. DMG actually has protective abilities against mutagens and carcinogens that may be in our food, water and the air we breathe.

Paul Buck, Ph. D., nutritional biochemist at an FDA approved laboratory in Waverly, NY, is quoted to have said that “the average person would have to ingest 21 pounds or more of DMG in a short amount of time for it to be toxic, and at that point it would be a problem more with the volume than with the actual toxicity of the DMG.”

Dr. Gary Todd, M.D., describes DMG safety in his book entitled Nutrition, Health and Disease on page 206. Dr. Todd summarizes the extreme safety of DMG with this illustration: “the average DMG tablet is 125 mg, so you would have to take 4,144 tablets in a single dose to achieve the LD₅₀ for the average 70 kg (154 lb.) male, which would cost you $1,167.23. The intake of this much DMG would take an impossibly long time to swallow all the tablets, so a toxic dose would be impossible in humans, considering it would take almost 50 liters of water to swallow the pills, which in itself is a lethal dose.”

Why Take DMG?

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Dimethylglycine is absolutely essential to virtually all human biological functions. DMG plays a key role in at least 41 different biochemical processes that are directly linked to how the body ages. DMG is required by all 70 trillion cells of the body for everything from proper nutrient absorption to cellular metabolism and energy production to oxygenation of the bloodstream. Dimethylglycine increases neuron activity and brain function, promotes healthy heart function, supports proper liver function and detoxification, enhances immune system function, and is generally essential to virtually all human biological function, including the production of DNA.

The body makes DMG, but not in sufficient levels to counter the many stress factors that assault the body today. Unfortunately, the body makes less and less dimethylglycine as we age. DMG is an anti-stress nutrient and metabolic enhancer, which provides a wide spectrum of benefits to health, vitality and wellness. It also has many healing and therapeutic benefits. Therefore, for optimal health, most people will notice significant improvement when taking DMG. The specific benefits that a person will receive from taking DMG are very unique to that person’s overall health, lifestyle, age and stress level.

How to Take DMG

Dimethylglycine is quickly broken down in the body, so smaller doses multiple times a day is best rather than taking it all at once. It is best to take DMG several times throughout the day in order to maintain consistent availability to the body. May be taken with out without food.

Dimethylglycine is best taken between meals to avoid competitive uptake from other amino acids although it can be taken with food as well. Individuals with heavy work schedules, high stress, athletes or people dealing with a major health problem can benefit from higher intakes of DMG. Depending on the specific area of use, the recommended dosage of DMG can range anywhere from 125mg to over 1000mg a day. An additional 150mg to 300mg can be taken for every 2 to 4 hours of exercise or heavy stress. Due to biochemical individuality, results can show up anywhere from a few days to a few weeks.

In Conclusion

DMG can help you live a longer, better and healthier life. It can add years to your life and life to your years. Dimethylglycine is a safe, effective and natural way to build wellness and optimize health. Taking DMG is a practical way to support well-being, cope with stress, slow the aging process and allow us to stay healthier by fortifying our body against dis-ease. Mountain Well-Being is the source for pure, high quality DMG packaged in convenient chewable tablets. Instead of the usual 60 count bottles, Mountain Well-Being DMG comes in packages containing a full 90 chewable tablets of dimethylglycine. At 250 mg per capsule, ours is double the strength as most other brands.

For an excellent book on the health benefits of DMG, please CLICK HERE.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.